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Frontline Plus for Medium Dogs 23-44 lbs (Blue)

$35.41
In Stock
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Frontline Plus for Medium Dogs 23-44 lbs (Blue)
$35.41
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Frontline Plus for Medium Dogs (Blue): Monthly Flea and Tick Treatment

Frontline Plus for Medium Dogs (Blue) is a convenient topical treatment widely used by pet parents to protect their dogs against fleas and ticks. This long-lasting, waterproof formula extends parasite protection for a full 30 days.

This vet-recommended flea and tick treatment kills parasites on contact, so no biting is required. It is suitable for dogs and puppies aged 8 weeks and above, and weighing between 23 & 44 lbs.

Why choose Frontline Plus for Medium Dogs (Blue)?

  • Kills fleas- including fleas which may cause flea allergy dermatitis, flea eggs and flea larvae
  • Prevents all flea stages (eggs, larvae, and pupae) from developing
  • Stops existing flea infestations and prevents the establishment of new infestations
  • Kills all life stages (larva, nymph, adult) of brown dog ticks, American dog ticks, lone star ticks, and deer ticks
  • Kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, haemobartonellosis, ehrlichiosis, babesiosis, anaplasmosis, and other tick-borne diseases
  • Rapidly eliminates chewing lice infestations
  • Aids in control of sarcoptic mange infestations

Frontline Plus for Medium Dogs (Blue): Fast-acting parasite treatment

Frontline Plus for medium dogs (blue) contains two active ingredients: Fipronil and (S)-methoprene. Both these ingredients spread from the single point of application and rapidly cover the dog’s entire coat. Frontline Plus localizes onto the skin and hair coat, where it keeps working continuously even if your dog gets wet. When fleas, ticks and lice come into contact with the treated dog, they get killed. These nasty parasites do not have to bite your dog in order to die.

Ingredients

Fipronil
(S)-methoprene

Why To Use Frontline Plus
  • Vet-recommended flea and tick treatment for dogs
  • Easy-to-apply, topical, spot-on treatment
  • Long-lasting and fast-acting formula
  • Waterproof treatment
  • Kills parasites on contact- no biting required
  • Can be used on dogs and puppies from 8 weeks of age and 5 lbs. of body weight
  • Available in different weight-specific doses for dogs of different sizes
Usage Directions For Frontline Plus
  • Frontline Plus is available in four different packs for weight-appropriate dosage in dogs of different sizes. The packs are available in color-coded boxes for easy identification and convenient selection.
  • Check your dog’s weight and get the pack that is appropriate for your dog’s body weight.
  • Use scissors to separate one blister. Cut along the dotted line, and then peel the foil to remove the applicator.
  • Hold the applicator upright with the foil side towards you and snap the applicator tip.
  • Part your dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze.
  • Apply the entire contents of the applicator in a single spot directly onto your dog’s skin.
  • Do not apply it on top of the hair coat.
  • Apply it on dry coat. Keep your dog’s coat dry for 24 hours after application.
  • Avoid contact with the treated area until dry.
  • Do not allow your dog to ingest the product.
  • Do not use more than one application per dog per month. Do not reapply Frontline Plus for 30 days.

Dosage:

Dog weight Pack color Applicator content
Up to 22 lbs. Orange 0.67 ml
23-44 lbs. Blue 1.34 ml
45-88 lbs. Purple 2.68 ml
Over 89 lbs. Red 4.02 ml
Frontline Plus Protective Measures

For animals:

  • For external use on dogs only. Do not use it on cats, rabbits or other animals.
  • Do not use on puppies less than 8 weeks of age and weighing less than 5 lbs.
  • Read the entire label and follow the directions for use.

For humans:

  • It is not for human use.
  • Keep out of reach of children. Do not allow children to apply the product.
  • Avoid contact with skin, eyes or clothing.
  • Wash your hands thoroughly with soap and water after handling the product and before eating, drinking, chewing gum or using tobacco.
  • It is harmful if swallowed. If accidentally swallowed, call a poison control center or doctor immediately for treatment advice. Sip a glass of water if able to swallow. Do not induce vomiting unless medically advised.
  • If in the eyes, hold the eye open and rinse gently with water for 15-20 minutes. If wearing contact lenses, remove them after the first 5 minutes and then continue rinsing your eyes. Call a poison control center or doctor for treatment advice.
  • If on skin or clothing, take off contaminated clothing. Rinse the skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice.

Precautions:

  • Consult a veterinarian before using it on medicated, debilitated or aged animals.

Storage & disposal:

  • Do not contaminate water, food, or feed by storage and disposal.
  • Do not use or store near heat or open flame.
  • Store unused product in original container, out of reach of children and animals.
  • Place the used container in the trash.
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Key Specifications
Suitability
Suitability

Recommended for puppies and dogs from 8 weeks of age & weighing at least 5 lbs

Active Ingredients
Active Ingredients

Fipronil
S-methoprene

Indications
Indications

Antiparasitic: Canine external parasites

Frontline Plus - A Popular Name in Canine Flea & Tick Protection

Frontline Plus promises superior dog healthcare. Here's why dog parents prefer this spot-on treatment:

Broad coverage
Broad coverage

Protects against fleas, ticks, lice & mites

Convenient
Convenient

Designed for easy & mess-free application

Long-lasting
Long-lasting

Provides a sustained flea & tick control for 30 days

Water-resistant
Water-resistant

Stays effective even after bathing or swimming

Safe & secure

Safe for dogs from 8 weeks including pregnant, breeding & lactating dogs

Quick Application : Just 30 Seconds, Every 30 Days

Administering Frontline Plus on your dog is simple. Follow these 4 easy steps to unleash the power of fipronil & s-methoprene.

Remove
Remove

Remove an applicator from the foil-backed holder.

Hold
Hold

Hold the pipette upright with the foil side toward you and snap the applicator tip.

Choose
Choose

Choose an area where the dog cannot lick, e.g. on the back of the neck between the shoulder blades. Part hair on the coat until the skin is visible.

Place
Place

Place the tip of the pipette on the skin & squeeze several times to empty the contents on the skin.

Frontline Plus: Fast-acting Flea & Tick Treatment

Frontline Plus contains fipronil and s-methoprene as active ingredients. This composition delivers comprehensive protection against external parasites, including fleas and ticks.

Fleas
Ticks
Lice
Mites
fleas
Fleas
  • Kills adult fleas, flea eggs & flea larvae
  • Prevents all flea life stages including eggs, larvae & pupae from developing
  • Eliminates existing flea infestations
  • Prevents new infestations from developing
  • Kills fleas that may cause flea allergy dermatitis (FAD)
ticks
Ticks
  • Effective against all tick life stages
  • Kills larvae, nymph & adult ticks
  • Protects against brown dog ticks, American dog ticks, lone star ticks & black-legged ticks ( deer ticks)
  • Kills ticks that may transmit Lyme disease, Ehrlichiosis, Haemobartonellosis, Rocky Mountain Spotted Fever, Babesiosis, Anaplasmosis & other tick-borne diseases
Lice
Lice
  • Quickly eliminates chewing lice infestations
  • Keeps killing chewing lice for at least one month
  • Ideal for use where effective lice control is needed
Mites
Mites
  • Aids in the control of sarcoptic mange infestations
  • Eliminates mites with multiple monthly treatments
Assorted Protection for Every Dog Size

Frontline Plus is formulated in various packs to suit dogs of all ages (from 8 weeks) and different weight ranges, from puppies to adults.

Frontline Plus is available in 3 and 6 doses packs, providing flexible dosing options depending on your dog's treatment requirements.

Frontline Plus for Dog Reviews

4.8

252 Reviews(s)

5 Star
81.75 %
4 Star
17.86 %
3 Star
0.4 %
2 Star
0 %
1 Star
0 %

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Grooming Day
Submitted by Fletcher on Sep 07, 2026
I usually pair this with grooming day, which helps me keep everything in one place.
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Home Routine
Submitted by Dashiell on Sep 02, 2026
Keeping this on hand makes it easier to stay prepared for my dog's regular care.
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Simple Care
Submitted by Merrick on Aug 31, 2026
It has been straightforward to include in my dog's regular preventive routine.
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Reliable Care
Submitted by Calloway on Aug 17, 2026
I've found it easy to stay consistent with this as part of my dog's routine.
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Outdoor Routine
Submitted by Rowan on Aug 10, 2026
It fits nicely into the care routine for my dog who spends plenty of time outside
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