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Heartgard Plus for Dogs

Rating: 4.5/5

In Stock, Ships Immediately,

Starting at Only: $22.07

Heartgard Plus

Heartgard Plus Chewables Small Dogs up to 25lbs (Blue)

Pack Size
6 Doses
12 Doses

Heartgard Plus Generic Nuheart Small Dogs upto 25lbs (Blue)

Pack Size
6 Tablet
12 Tablet

Heartgard Plus Chewables for Medium Dogs 26-50lbs (Green)

Pack Size
6 Doses
12 Doses

Heartgard Plus Generic Nuheart Medium Dogs 26-50lbs (Green)

Pack Size
6 Tablet
12 Tablet

Heartgard Plus Chewables for Large Dog 51-100lbs (Brown)

Pack Size
6 Doses
12 Doses

Heartgard Plus Generic Nuheart for Large Dogs 51-100lbs (Red)

Pack Size
6 Tablet
12 Tablet

Heartgard Plus Chewable Tablet for Dogs

Heartgard Plus for Dogs is a trusted preventative for heartworm disease. It offers a simple yet effective solution to safeguard your furry friend's health. This chewable tablet is formulated to prevent canine heartworm disease by targeting the tissue stage of heartworm larvae for a month. It also effectively treats and controls roundworms (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense). With a real-beef flavor that dogs love, administering Heartgard Plus Chews is a breeze. It is a monthly heartworm treatment for dogs and puppies 6 weeks of age and older. Plus, it's safe for use in breeding or pregnant dogs, providing peace of mind for pet parents.

Heartgard Plus (ivermectin/pyrantel) - A Broad Spectrum Heartworm Preventive For Dogs

Heartgard Plus for Dogs contains ivermectin and pyrantel as its active ingredients. Ivermectin works by interfering with the nerve impulses in parasites, ultimately causing their paralysis and death. This prevents the development of heartworm larvae into adult worms and also helps in eliminating other internal parasites. Pyrantel works by paralyzing and killing roundworms and hookworms, ensuring comprehensive protection against intestinal parasites. Together, these ingredients provide effective and reliable protection for your dog's health.

Nuheart Heartworm Tablets

Nuheart Heartworm Tablets offer effective prevention against heartworm disease in dogs, serving as a generic alternative to Heartgard. With the same active ingredient, Ivermectin, Nuheart destroys heartworm larvae and controls heartworm disease without any adverse effects. Featuring a unique three-way delivery system, Nuheart ensures easy dosing with its small size, enticing sweet meat flavor, and solubility for added convenience. Protect your canine companion effortlessly with Nuheart, the trusted choice for heartworm prevention.


Heartgard Plus: Ivermectin, Pyrantel

Nuheart: Ivermectin

Why To Use Heartgard Plus
  • Prevents heartworm disease in dogs
  • Treats and controls roundworms and hookworms
  • Real-beef flavored chewable tablet easily accepted by dogs
  • Provides continuous protection against heartworm disease for one month
  • Helps maintain your dog's overall health and well-being
  • Palatable formulation ensures hassle-free administration
  • Trusted by veterinarians for its proven efficacy
  • Safe for use in dogs 6 weeks of age and older, including breeding or pregnant dogs
Usage Directions For Heartgard Plus
  • Weigh your pet and choose an appropriate pack size.
  • Remove only one chewable at a time from the foil-backed blister card.
  • After use, return the card with the remaining chewables to its box to protect the product from light.
  • Offer the chewable to the dog by hand.
  • Administer the chewable at monthly intervals on the same day of each month throughout the year.
  • Encourage the dog to chew the chewable to avoid the risk of choking or intestinal obstruction.
  • If necessary, break the chewable into pieces for dogs that swallow treats whole.
  • Alternatively, add the chewable intact to a small amount of dog food to encourage chewing, ensuring the dog consumes the complete dose at one time.


Dog Weight

Pack Color

Ivermectin Content

Pyrantel Content

Monthly Dose

0 to 25 lbs


68 mcg

57 mg

One Chew

26 to 50 lbs


136 mcg

114 mg

One Chew

51 to 100 lbs


272 mcg

227 mg

One Chew

Over 100 lbs

Use an appropriate combination of chewables

Heartgard Plus Protective Measures
  • Not recommended for dogs younger than 6 weeks of age.
  • Keep this and all drugs out of reach of children.
  • Dogs should be tested for existing heartworm infection prior to starting the treatment.
  • Do not skip the dosage in winters as it can make your pooch vulnerable to heartworm infestation.
  • Consult your vet if you miss the treatment for two months continuously.


Collies including Border Collies and other breeds have a genetic intolerance to Ivermectin. Those pet parents with Collies and other susceptible breeds should look for alternatives to Ivermectin for the treatment of parasites.

Q. Is Heartgard Plus safe for all dogs?

A. Yes, Heartgard Plus is safe for most dogs from 6 weeks of age. However, it's always best to consult your veterinarian before starting any new medication.

Q. How often should I administer Heartgard Plus to my dog?

A. Heartgard Plus should be given once a month, on the same day each month, to ensure continuous protection.

Q. Is there an age or weight requirement for Heartgard Plus?

A. Heartgard Plus is recommended for dogs that are at least 6 weeks old and weigh at least 2 pounds.

Q. Can pregnant or nursing dogs take Heartgard Plus?

A. Yes, Heartgard Plus is safe for use in pregnant or nursing dogs.

Q. What should I do if my dog misses a dose of Heartgard Plus?

A. If your dog misses a dose, give the missed dose as soon as you remember and then continue with the regular monthly schedule. In case of more than 2 months of skipped dose, consult your vet.

Q. How does Heartgard Plus compare to other heartworm preventatives?

A. Compared to other heartworm preventatives, Heartgard Plus also treats and controls roundworms and hookworms, providing broader protection.

Q. How is Heartgard Plus administered?

A. Heartgard Plus is given orally once a month. It comes in a chewable tablet that most dogs find palatable.

Q. Should I test my dog for heartworms before starting Heartgard Plus?

A. Yes, it's important to have your dog tested for heartworms before beginning Heartgard Plus, as administering it to a dog with an existing heartworm infection can cause complications.

Q. Are there any side effects associated with Heartgard Plus?

A. Side effects are rare, but some dogs may experience vomiting, diarrhea, or lethargy. Always monitor your dog after administering any medication.

Q. In what sizes and options are Heartgard Plus Chewables available?

A. Heartgard Plus Chewables come in different dosages based on the weight of your dog, ensuring the correct amount of medication for effective treatment.

Q. Is Heartgard Plus expensive?

A. The cost of Heartgard Plus can vary, but it's generally considered affordable, especially given its broad spectrum of protection.

Q. Are there any cheaper alternatives to Heartgard Plus?

Yes, there are generic alternatives to Heartgard Plus that may be less expensive, but it's important to consult your vet before switching medications.

Q. What if my dog won't eat the Heartgard Plus chew?

A. If your dog refuses the chew, you can try hiding it in a small amount of food or breaking it into smaller pieces.

Q. What should I do if my dog vomits after taking Heartgard Plus?

A. If your dog vomits within an hour of taking Heartgard Plus, consult your veterinarian as they may recommend administering another dose.

Q. Are there any generic versions of Heartgard Plus available?

A. Yes, there are generic versions of Heartgard Plus that contain the same active ingredients and offer similar protection. For heartworm protection you can discuss Nuheart Heartworm Tablets, a generic version of Heartgard with your vet. Always consult your veterinarian before making any changes to your dog's medication.

Q. What is the price range for Heartgard Plus?

A. Heartgard Plus for Dogs price can vary depending on the retailer and the dosage required for your dog’s weight. It is generally affordable and can often be found at competitive prices online through PetCareClub.

Q. How do customers review Heartgard Plus?

A. Heartgard Plus reviews are highly rated by pet parents for its effectiveness in preventing heartworm disease and treating intestinal parasites. Many reviews highlight its palatable taste, ease of administration, and overall reliability in keeping dogs healthy.

Customer Reviews
Super effective

I have been using it for long. A perfect heartworm preventive for my baby.

Excellent Product

It helps us to keep our fidos protected against heartworms.

Heartworm Prevention

Best guard for heartworm disease is only Heartgard Plus! Just give it a try.

Acceptable taste

An easy to dose heartworm preventive. My pet likes the taste.