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Simparica Chewables for Dogs 22.1-44 lbs (Blue)

$72.58
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Simparica Chewables for Dogs 22.1-44 lbs (Blue)
$72.58
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Simparica for Dogs (Blue): Monthly Flea & Tick Treatment

Give your dog faster relief from parasite infestations with Simparica flea and tick treatment (blue), a monthly chewable that stays strong all month long. The protection of this oral treatment extends to 35 days, giving you a leeway period in case you are a little late giving the dose to your dog.

This great-tasting, flavored chewable tablet is easy to administer and is suitable for dogs aged 6 months and above, and weighing between 22.1 & 44 lbs.

Why choose Simparica for dogs (blue)?

  • Kills adult fleas before they can lay eggs
  • Treats and prevents flea infestations
  • Treats and controls tick infestations caused by lone star ticks, Gulf Coast ticks, American dog ticks, black-legged ticks, brown dog ticks, and Asian longhorned ticks
  • Helps prevent infections that may cause Lyme disease, by killing deer ticks/black-legged ticks

Simparica for Dogs (Blue): Fast-acting parasite treatment

Simparica (blue) contains sarolaner, a powerful insecticide. It causes uncontrolled neuromuscular activity in parasites, leading to their death. This chewable tablet begins to kill fleas within 3 hours, and ticks within 8 hours after initial administration (as per Zoetis studies) and provides your dog with quick relief from parasite infestations.

Ingredients

Sarolaner

Why To Use Simparica Chewables
  • Vet-recommended flea and tick treatment for dogs
  • Great-tasting, flavored chewable tablet
  • Convenient monthly dosage
  • Stays strong all month long
  • Gives a leeway period in case you are a little late administering the dosage
  • Fast-action formula
  • Can be given to dogs from 6 months of age and 2.8 lbs. of body weight
  • Available in weight-specific doses for dogs of different sizes
Usage Directions For Simparica Chewables
  • Simparica Chewable Tablets are available in six different packs for weight-appropriate dosage in dogs of different sizes. The packs are available in color-coded boxes for easy identification and convenient selection.
  • Check your dog’s weight and get the pack that is appropriate for your dog’s body weight.
  • Administer the chewable to your dog orally once a month.
  • It can be offered by hand, given in the food, or administered like other tablet treatments.
  • Ensure that your dog consumes the complete dose.
  • Observe your treated dog for a few minutes to ensure that part of the dose is not lost or refused.
  • If you miss a dose, administer Simparica and resume the monthly dosing schedule.
  • To minimize the likelihood of flea re-infestation, it is recommended to treat all pets in the household with a flea treatment.

Dosage guide:

Dog weight (lbs.) Pack color Sarolaner per tablet (mg) No of tablets administered (monthly)
2.8 – 5.5 Yellow 5 One
5.6 – 11 Purple 10 One
11.1 – 22 Caramel 20 One
22.1 – 44 Blue 40 One
44.1 – 88 Green 80 One
88.1 – 132* Brown 120 One

*For dogs weighing over 132.1 lbs.: Administer the appropriate combination of tablets.

Simparica Chewables Protective Measures

For animals:

  • For use in dogs only. Do not use it in cats.
  • Do not use in dogs less than 6 months of age.
  • Read the entire label and follow the safety directions.

For humans:

  • It is not for human use.
  • Keep out of reach of children.

Precautions

  • Use with caution in dogs with a history of seizures or neurologic disorders.
  • Consult a veterinarian before using it in breeding, pregnant or lactating dogs.

Storage & disposal

  • Keep Simparica in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose.
  • Store at or below 86°F (30°C) with excursions permitted up to 104°F (40°C).
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Simparica – Quick-Acting, Lasting Protection

Simparica offers fast-acting, long-lasting protection against fleas, ticks and Lyme disease. Suitable for dogs of all sizes, including puppies as young as 6 months and weighing 2.8 lbs or more. Its tasty chewable formula makes protection easy and enjoyable for your pup!

Advantages of Simparica
Palatable Flavored Chewables

Tasty chews your dog loves, making protection feel like a treat!

Starts Killing Ticks within 8 Hours

Fast action ensures your dog gets tick-free in no time.

Starts Killing Fleas within 3 Hours

Quick relief from fleas, keeping your pup comfortable and itch-free.

Month-long Protection without Losing Effectiveness

Reliable defense that stays strong for 30 days, no interruptions.

Comprehensive Tick Defense

Effective against a variety of ticks, including lone star tick, Gulf Coast tick, American dog tick, black-legged tick, brown dog tick, and Asian longhorned tick.

Kills Deer Ticks, Blocking Infections That Cause Lyme Disease

Protects your dog from harmful infections by eliminating disease-carrying ticks.

Powered by Trusted Ingredients for Superior Protection!

Simparica is formulated with sarolaner, a trusted ingredient that delivers fast-acting, long-lasting protection against fleas and ticks. Its powerful, vet-approved formula ensures month-long effectiveness, keeping your dog safe and healthy with every chew.

Flea Protection

Simparica delivers rapid relief for pets suffering from flea infestations, starting to kill fleas within just 3 hours. It eliminates nearly all fleas within 8 hours, reducing live fleas by ≥96.2% for up to 35 days.

Tackling Home Flea Infestations

Simparica is your trusted solution to prevent or quickly eliminate fleas in your home.

Proven Performance

In a simulated flea-infested home environment, monthly Simparica treatment for 3 months achieved over 95.6% reduction in adult fleas within 14 days and 100% elimination from day 60 to day 90 of the study.

Breaks the Flea Life Cycle

Simparica stops fleas before they can reproduce. In lab tests, dogs treated with Simparica produced no viable flea eggs just one day after treatment, maintaining this effect for the full 35-day observation period.

Tick Protection

Simparica provides reliable, month-long tick control with no gaps in coverage.

In controlled laboratory studies, Simparica chewables achieved ≥96.9% effectiveness for 35 days against various tick species, including black-legged tick (Ixodes scapularis), lone star tick (Amblyomma americanum), Gulf-coast tick (Amblyomma maculatum), American dog tick (Dermacentor variabilis), brown dog tick (Rhipicephalus sanguineus) and Asian longhorned tick (Haemaphysalis longicornis).

Simparica works fast to kill ticks, reducing the risk of tick-borne diseases. In a clinical study, a single oral dose (2 mg/kg) effectively blocked the transmission of Lyme disease pathogens from deer ticks.

Tick Prevalence Maps

Ticks can show up anywhere. With the help of migrating birds, animal movements, climate changes, and human activity, ticks are quickly expanding their territory.

Check out the maps below from the Centers for Disease Control and Prevention (CDC), illustrating the expected spread of the lone star tick, Gulf Coast tick, American dog tick, and brown dog tick. The CDC also notes that these ticks may be found beyond the marked regions.

A. Maculatum Gulf Coast Tick
A. americanum (Lone Star tick)
D. variabilis (American Dog tick)
I. scapularis (Deer tick or Black-legged tick)
R. sanguineus (Brown Dog tick)

Simparica offers a satisfaction guarantee, providing reliable protection against parasites. With its proven effectiveness, Simparica delivers fast-acting protection against fleas, ticks, and Lyme disease. Pet parents can trust Simparica for reliable, long-lasting defense, keeping their pets safe and healthy year-round.

Tailored Protection for Every Dog

Available in multiple pack sizes to fit dogs of all ages and sizes, from puppies to seniors.

Each tablet size comes in packs of three or six chewable tablets, offering a 3-month or 12-month supply, respectively.

These options guarantee precise and effective dosing for dogs of all sizes, ensuring complete protection.

Simparica Chewables for Dog Reviews

4.7

210 Reviews(s)

5 Star
68.1 %
4 Star
31.9 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

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Handy Pack
Submitted by Rowan on Sep 13, 2026
The packaging is convenient to keep with the rest of my dog's supplies.
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Easy Handling
Submitted by Kairo on Sep 01, 2026
The chew is simple to handle and makes dosing convenient for me.
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Easy Giving
Submitted by Dax on Aug 30, 2026
My dog accepts the chew without any fuss, making treatment days much easier.
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Simple Dosing
Submitted by Rafferty on Aug 23, 2026
My dog accepts the chew without needing any tricks or hiding it in food.
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Easy Dosing
Submitted by Zayden on Aug 16, 2026
My dog takes the chew willingly, which makes regular dosing convenient
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